| Puerto del Rosario to Southern Pines (North Carolina) | 3,805.80 mi (6,124.85 km) |
| Puerto del Rosario to Southfield (Michigan) | 3,911.35 mi (6,294.71 km) |
| Puerto del Rosario to Southgate (Michigan) | 3,911.83 mi (6,295.48 km) |
| Puerto del Rosario to Southlake (Texas) | 4,820.57 mi (7,757.96 km) |
| Puerto del Rosario to Spanaway (Washington) | 5,585.72 mi (8,989.34 km) |
| Puerto del Rosario to Spanish Fork (Utah) | 5,354.49 mi (8,617.21 km) |
| Puerto del Rosario to Spanish Lake (Missouri) | 4,323.13 mi (6,957.40 km) |
| Puerto del Rosario to Spanish Springs (Nevada) | 5,741.14 mi (9,239.47 km) |
| Puerto del Rosario to Sparks (Nevada) | 5,746.27 mi (9,247.73 km) |
| Puerto del Rosario to Spartanburg (South Carolina) | 3,948.49 mi (6,354.48 km) |
| Puerto del Rosario to Spearfish (South Dakota) | 4,866.27 mi (7,831.51 km) |
| Puerto del Rosario to Speedway (Indiana) | 4,100.76 mi (6,599.54 km) |
| Puerto del Rosario to Spencer (Iowa) | 4,487.44 mi (7,221.83 km) |
| Puerto del Rosario to Spokane (Washington) | 5,364.98 mi (8,634.10 km) |
| Puerto del Rosario to Spokane Valley (Washington) | 5,357.05 mi (8,621.34 km) |
