| Pueblo West to Orangeburg (South Carolina) | 1,372.16 mi (2,208.28 km) |
| Pueblo West to Orangevale (California) | 890.90 mi (1,433.76 km) |
| Pueblo West to Orchards (Washington) | 1,042.04 mi (1,677.00 km) |
| Pueblo West to Orcutt (California) | 901.91 mi (1,451.48 km) |
| Pueblo West to Oregon (Ohio) | 1,146.78 mi (1,845.57 km) |
| Pueblo West to Oregon (Wisconsin) | 862.48 mi (1,388.03 km) |
| Pueblo West to Oregon City (Oregon) | 1,035.76 mi (1,666.89 km) |
| Pueblo West to Orem (Utah) | 396.30 mi (637.79 km) |
| Pueblo West to Orinda (California) | 947.99 mi (1,525.64 km) |
| Pueblo West to Orland Park (Illinois) | 919.15 mi (1,479.23 km) |
| Pueblo West to Orlando (Florida) | 1,505.42 mi (2,422.73 km) |
| Pueblo West to Ormond Beach (Florida) | 1,487.40 mi (2,393.74 km) |
| Pueblo West to Oro Valley (Arizona) | 539.77 mi (868.67 km) |
| Pueblo West to Oroville (California) | 907.32 mi (1,460.19 km) |
| Pueblo West to Oshkosh (Wisconsin) | 925.32 mi (1,489.16 km) |
