| Pueblo West to Enterprise (Nevada) | 599.95 mi (965.53 km) |
| Pueblo West to Enumclaw (Washington) | 1,064.40 mi (1,712.99 km) |
| Pueblo West to Ephrata (Pennsylvania) | 1,525.59 mi (2,455.20 km) |
| Pueblo West to Erie (Colorado) | 118.25 mi (190.30 km) |
| Pueblo West to Erie (Pennsylvania) | 1,321.29 mi (2,126.41 km) |
| Pueblo West to Erlanger (Kentucky) | 1,084.98 mi (1,746.11 km) |
| Pueblo West to Escanaba (Michigan) | 1,036.02 mi (1,667.31 km) |
| Pueblo West to Escondido (California) | 779.55 mi (1,254.57 km) |
| Pueblo West to Española (New Mexico) | 177.93 mi (286.35 km) |
| Pueblo West to Essex (Maryland) | 1,517.49 mi (2,442.16 km) |
| Pueblo West to Essex Junction (Vermont) | 1,680.47 mi (2,704.45 km) |
| Pueblo West to Estelle (Louisiana) | 1,020.19 mi (1,641.83 km) |
| Pueblo West to Estero (Florida) | 1,564.21 mi (2,517.36 km) |
| Pueblo West to Euclid (Ohio) | 1,245.15 mi (2,003.87 km) |
| Pueblo West to Eufaula (Alabama) | 1,189.15 mi (1,913.75 km) |
