| Pueblo to Storm Lake (Iowa) | 579.40 mi (932.45 km) |
| Pueblo to Storrs (Connecticut) | 1,718.83 mi (2,766.18 km) |
| Pueblo to Stoughton (Wisconsin) | 867.40 mi (1,395.94 km) |
| Pueblo to Stow (Ohio) | 1,244.13 mi (2,002.23 km) |
| Pueblo to Streamwood (Illinois) | 904.15 mi (1,455.09 km) |
| Pueblo to Streator (Illinois) | 860.54 mi (1,384.91 km) |
| Pueblo to Streetsboro (Ohio) | 1,248.87 mi (2,009.87 km) |
| Pueblo to Strongsville (Ohio) | 1,223.85 mi (1,969.60 km) |
| Pueblo to Stuart (Florida) | 1,602.56 mi (2,579.08 km) |
| Pueblo to Stuarts Draft (Virginia) | 1,385.42 mi (2,229.62 km) |
| Pueblo to Sturgis (Michigan) | 1,041.80 mi (1,676.62 km) |
| Pueblo to Suamico (Wisconsin) | 960.51 mi (1,545.79 km) |
| Pueblo to Sudley (Virginia) | 1,460.66 mi (2,350.71 km) |
| Pueblo to Suffern (New York) | 1,623.46 mi (2,612.70 km) |
| Pueblo to Suffolk (Virginia) | 1,531.65 mi (2,464.95 km) |
