| Pueblo to Silver Firs (Washington) | 1,101.62 mi (1,772.89 km) |
| Pueblo to Silver Spring (Maryland) | 1,484.23 mi (2,388.64 km) |
| Pueblo to Silver Springs Shores (Florida) | 1,439.66 mi (2,316.91 km) |
| Pueblo to Silverdale (Washington) | 1,116.36 mi (1,796.61 km) |
| Pueblo to Silverton (Oregon) | 1,044.04 mi (1,680.22 km) |
| Pueblo to Simi Valley (California) | 833.68 mi (1,341.67 km) |
| Pueblo to Simpsonville (South Carolina) | 1,262.21 mi (2,031.33 km) |
| Pueblo to Sioux City (Iowa) | 521.60 mi (839.43 km) |
| Pueblo to Sioux Falls (South Dakota) | 549.00 mi (883.53 km) |
| Pueblo to Skokie (Illinois) | 926.42 mi (1,490.92 km) |
| Pueblo to Sleepy Hollow (New York) | 1,637.57 mi (2,635.41 km) |
| Pueblo to Slidell (Louisiana) | 1,008.35 mi (1,622.79 km) |
| Pueblo to Smithfield (North Carolina) | 1,458.68 mi (2,347.52 km) |
| Pueblo to Smithfield (Utah) | 453.93 mi (730.53 km) |
| Pueblo to Smithville (Missouri) | 545.45 mi (877.82 km) |
