| Prudhoe to Olympia Heights (Florida) | 4,332.45 mi (6,972.40 km) |
| Prudhoe to Omaha (Nebraska) | 4,107.34 mi (6,610.12 km) |
| Prudhoe to On Top of the World Designated Place (Florida) | 4,229.22 mi (6,806.27 km) |
| Prudhoe to Onalaska (Wisconsin) | 3,806.57 mi (6,126.09 km) |
| Prudhoe to Oneida (New York) | 3,279.17 mi (5,277.31 km) |
| Prudhoe to Oneonta (New York) | 3,285.19 mi (5,287.00 km) |
| Prudhoe to Ontario (California) | 5,211.70 mi (8,387.42 km) |
| Prudhoe to Ontario (Oregon) | 4,616.33 mi (7,429.27 km) |
| Prudhoe to Opa-locka (Florida) | 4,319.76 mi (6,951.98 km) |
| Prudhoe to Opelika (Alabama) | 4,162.29 mi (6,698.56 km) |
| Prudhoe to Opelousas (Louisiana) | 4,529.26 mi (7,289.13 km) |
| Prudhoe to Orange (California) | 5,232.05 mi (8,420.17 km) |
| Prudhoe to Orange (Texas) | 4,613.76 mi (7,425.12 km) |
| Prudhoe to Orange City (Florida) | 4,199.24 mi (6,758.02 km) |
| Prudhoe to Orangeburg (South Carolina) | 3,945.91 mi (6,350.33 km) |
