| Prudhoe to Savignano sul Rubicone | 982.29 mi (1,580.85 km) |
| Prudhoe to Savona | 867.14 mi (1,395.53 km) |
| Prudhoe to Scafati | 1,234.46 mi (1,986.67 km) |
| Prudhoe to Scalea | 1,324.93 mi (2,132.27 km) |
| Prudhoe to Scandiano | 906.06 mi (1,458.16 km) |
| Prudhoe to Scandicci | 968.20 mi (1,558.16 km) |
| Prudhoe to Schio | 861.82 mi (1,386.96 km) |
| Prudhoe to Sciacca | 1,394.70 mi (2,244.56 km) |
| Prudhoe to Scicli | 1,478.27 mi (2,379.04 km) |
| Prudhoe to Scordia | 1,450.66 mi (2,334.61 km) |
| Prudhoe to Scorze | 891.74 mi (1,435.12 km) |
| Prudhoe to Sedico | 862.25 mi (1,387.65 km) |
| Prudhoe to Sedriano | 808.85 mi (1,301.73 km) |
| Prudhoe to Segni | 1,138.68 mi (1,832.53 km) |
| Prudhoe to Segrate | 817.00 mi (1,314.83 km) |
