| Prineville to Southern Pines (North Carolina) | 2,264.14 mi (3,643.79 km) |
| Prineville to Southfield (Michigan) | 1,875.60 mi (3,018.48 km) |
| Prineville to Southgate (Michigan) | 1,883.79 mi (3,031.67 km) |
| Prineville to Southlake (Texas) | 1,492.48 mi (2,401.91 km) |
| Prineville to Spanaway (Washington) | 207.59 mi (334.08 km) |
| Prineville to Spanish Fork (Utah) | 553.06 mi (890.06 km) |
| Prineville to Spanish Lake (Missouri) | 1,620.03 mi (2,607.19 km) |
| Prineville to Spanish Springs (Nevada) | 326.48 mi (525.43 km) |
| Prineville to Sparks (Nevada) | 331.71 mi (533.83 km) |
| Prineville to Spartanburg (South Carolina) | 2,147.98 mi (3,456.85 km) |
| Prineville to Spearfish (South Dakota) | 840.10 mi (1,352.00 km) |
| Prineville to Speedway (Indiana) | 1,789.30 mi (2,879.60 km) |
| Prineville to Spencer (Iowa) | 1,280.85 mi (2,061.33 km) |
| Prineville to Spokane (Washington) | 284.99 mi (458.64 km) |
| Prineville to Spokane Valley (Washington) | 290.34 mi (467.25 km) |
