| Prienai to Ruzomberok | 431.51 mi (694.45 km) |
| Prienai to Sabinov | 400.77 mi (644.98 km) |
| Prienai to Sal'a | 518.21 mi (833.98 km) |
| Prienai to Samorin | 538.26 mi (866.24 km) |
| Prienai to Senec | 524.71 mi (844.45 km) |
| Prienai to Senica | 498.12 mi (801.64 km) |
| Prienai to Sered' | 513.02 mi (825.62 km) |
| Prienai to Skalica | 492.12 mi (791.99 km) |
| Prienai to Smizany | 418.39 mi (673.34 km) |
| Prienai to Snina | 397.39 mi (639.54 km) |
| Prienai to Spisska Nova Ves | 418.59 mi (673.66 km) |
| Prienai to Stara L'ubovna | 393.08 mi (632.60 km) |
| Prienai to Stara Tura | 484.62 mi (779.91 km) |
| Prienai to Stropkov | 387.50 mi (623.61 km) |
| Prienai to Stupava | 530.04 mi (853.02 km) |
