| Prestwick to Scottsboro (Alabama) | 3,970.16 mi (6,389.35 km) |
| Prestwick to Scottsdale (Arizona) | 4,940.18 mi (7,950.45 km) |
| Prestwick to Scranton (Pennsylvania) | 3,241.98 mi (5,217.46 km) |
| Prestwick to Seabrook (Maryland) | 3,402.94 mi (5,476.51 km) |
| Prestwick to Seabrook (Texas) | 4,575.39 mi (7,363.38 km) |
| Prestwick to Seaford (New York) | 3,193.64 mi (5,139.66 km) |
| Prestwick to Seagoville (Texas) | 4,465.07 mi (7,185.84 km) |
| Prestwick to Seal Beach (California) | 5,134.43 mi (8,263.07 km) |
| Prestwick to Searcy (Arkansas) | 4,151.28 mi (6,680.83 km) |
| Prestwick to Seaside (California) | 5,079.49 mi (8,174.64 km) |
| Prestwick to SeaTac (Washington) | 4,462.94 mi (7,182.41 km) |
| Prestwick to Seattle (Washington) | 4,453.46 mi (7,167.15 km) |
| Prestwick to Sebastian (Florida) | 4,115.91 mi (6,623.91 km) |
| Prestwick to Sebring (Florida) | 4,169.98 mi (6,710.94 km) |
| Prestwick to Secaucus (New Jersey) | 3,210.29 mi (5,166.46 km) |
