| Prestwick to Stannington | 190.59 mi (306.73 km) |
| Prestwick to Stansted Mountfitchet | 316.92 mi (510.04 km) |
| Prestwick to Stanwell | 326.80 mi (525.93 km) |
| Prestwick to Stapleford | 222.80 mi (358.55 km) |
| Prestwick to Staveley | 202.26 mi (325.51 km) |
| Prestwick to Stepney | 332.82 mi (535.62 km) |
| Prestwick to Stevenage | 306.85 mi (493.82 km) |
| Prestwick to Stevenston | 11.75 mi (18.91 km) |
| Prestwick to Stirling | 50.33 mi (80.99 km) |
| Prestwick to Stockport | 174.91 mi (281.49 km) |
| Prestwick to Stocksbridge | 184.86 mi (297.50 km) |
| Prestwick to Stockton-on-Tees | 145.26 mi (233.77 km) |
| Prestwick to Stoke Gifford | 287.67 mi (462.97 km) |
| Prestwick to Stoke-on-Trent | 198.37 mi (319.25 km) |
| Prestwick to Stone | 205.11 mi (330.09 km) |
