| Prestwick to Shotley Bridge | 116.92 mi (188.17 km) |
| Prestwick to Shrewsbury | 206.80 mi (332.82 km) |
| Prestwick to Sidcup | 341.44 mi (549.49 km) |
| Prestwick to Sidmouth | 337.57 mi (543.26 km) |
| Prestwick to Sileby | 238.00 mi (383.03 km) |
| Prestwick to Sittingbourne | 361.79 mi (582.24 km) |
| Prestwick to Skegness | 257.41 mi (414.26 km) |
| Prestwick to Skelmersdale | 153.30 mi (246.71 km) |
| Prestwick to Skipton | 148.18 mi (238.48 km) |
| Prestwick to Sleaford | 241.98 mi (389.43 km) |
| Prestwick to Slough | 321.23 mi (516.98 km) |
| Prestwick to Small Heath | 237.62 mi (382.41 km) |
| Prestwick to Smethwick | 233.59 mi (375.93 km) |
| Prestwick to Snaresbrook | 330.07 mi (531.20 km) |
| Prestwick to Snodland | 355.27 mi (571.75 km) |
