| Prestwick to Spello | 1,157.55 mi (1,862.89 km) |
| Prestwick to Spilamberto | 1,022.65 mi (1,645.80 km) |
| Prestwick to Spilimbergo | 996.33 mi (1,603.44 km) |
| Prestwick to Spinea | 1,005.72 mi (1,618.55 km) |
| Prestwick to Spoleto | 1,171.01 mi (1,884.55 km) |
| Prestwick to Spoltore | 1,231.27 mi (1,981.54 km) |
| Prestwick to Spresiano | 993.42 mi (1,598.76 km) |
| Prestwick to Squinzano | 1,464.51 mi (2,356.90 km) |
| Prestwick to Statte | 1,430.36 mi (2,301.94 km) |
| Prestwick to Stezzano | 920.96 mi (1,482.14 km) |
| Prestwick to Strada | 1,084.57 mi (1,745.45 km) |
| Prestwick to Stradella | 942.44 mi (1,516.71 km) |
| Prestwick to Striano | 1,336.36 mi (2,150.67 km) |
| Prestwick to Subiaco | 1,229.79 mi (1,979.16 km) |
| Prestwick to Sulmona | 1,247.59 mi (2,007.80 km) |
