| Prestwick to Selargius | 1,288.79 mi (2,074.11 km) |
| Prestwick to Selvazzano Dentro | 999.71 mi (1,608.88 km) |
| Prestwick to Senago | 909.67 mi (1,463.97 km) |
| Prestwick to Senigallia | 1,133.91 mi (1,824.86 km) |
| Prestwick to Seravezza | 1,030.13 mi (1,657.83 km) |
| Prestwick to Seregno | 907.87 mi (1,461.08 km) |
| Prestwick to Seriate | 921.00 mi (1,482.20 km) |
| Prestwick to Sermoneta | 1,248.41 mi (2,009.12 km) |
| Prestwick to Serramanna | 1,272.82 mi (2,048.41 km) |
| Prestwick to Serravalle Pistoiese | 1,052.80 mi (1,694.31 km) |
| Prestwick to Sessa Aurunca | 1,294.00 mi (2,082.50 km) |
| Prestwick to Sesto Calende | 887.10 mi (1,427.64 km) |
| Prestwick to Sesto Fiorentino | 1,067.10 mi (1,717.33 km) |
| Prestwick to Sesto San Giovanni | 915.32 mi (1,473.06 km) |
| Prestwick to Sestri Levante | 991.19 mi (1,595.16 km) |
