| Prestonpans to Olympia Heights (Florida) | 4,282.03 mi (6,891.27 km) |
| Prestonpans to Omaha (Nebraska) | 4,035.89 mi (6,495.14 km) |
| Prestonpans to On Top of the World Designated Place (Florida) | 4,174.50 mi (6,718.20 km) |
| Prestonpans to Onalaska (Wisconsin) | 3,735.83 mi (6,012.23 km) |
| Prestonpans to Oneida (New York) | 3,217.34 mi (5,177.81 km) |
| Prestonpans to Oneonta (New York) | 3,224.33 mi (5,189.05 km) |
| Prestonpans to Ontario (California) | 5,134.40 mi (8,263.03 km) |
| Prestonpans to Ontario (Oregon) | 4,536.93 mi (7,301.49 km) |
| Prestonpans to Opa-locka (Florida) | 4,269.28 mi (6,870.74 km) |
| Prestonpans to Opelika (Alabama) | 4,102.53 mi (6,602.38 km) |
| Prestonpans to Opelousas (Louisiana) | 4,466.28 mi (7,187.79 km) |
| Prestonpans to Orange (California) | 5,154.74 mi (8,295.76 km) |
| Prestonpans to Orange (Texas) | 4,549.92 mi (7,322.38 km) |
| Prestonpans to Orange City (Florida) | 4,145.47 mi (6,671.49 km) |
| Prestonpans to Orangeburg (South Carolina) | 3,888.83 mi (6,258.47 km) |
