| Preston to Sesena | 944.65 mi (1,520.27 km) |
| Preston to Sestao | 722.04 mi (1,162.00 km) |
| Preston to Sevilla | 1,152.11 mi (1,854.14 km) |
| Preston to Sevilla La Nueva | 928.71 mi (1,494.62 km) |
| Preston to Silla | 1,000.54 mi (1,610.21 km) |
| Preston to Silleda | 804.83 mi (1,295.25 km) |
| Preston to Sitges | 890.11 mi (1,432.49 km) |
| Preston to Socuellamos | 999.49 mi (1,608.53 km) |
| Preston to Soller | 999.25 mi (1,608.13 km) |
| Preston to Solsona | 835.63 mi (1,344.82 km) |
| Preston to Son Servera | 1,017.27 mi (1,637.13 km) |
| Preston to Sonseca | 973.15 mi (1,566.13 km) |
| Preston to Sopelana | 717.14 mi (1,154.12 km) |
| Preston to Soria | 828.66 mi (1,333.59 km) |
| Preston to Suances | 716.07 mi (1,152.40 km) |
