| Preston to Sangeorgiu de Mures | 1,291.60 mi (2,078.63 km) |
| Preston to Sangeorz-Bai | 1,270.52 mi (2,044.70 km) |
| Preston to Sannicolau Mare | 1,158.18 mi (1,863.91 km) |
| Preston to Santana | 1,181.49 mi (1,901.43 km) |
| Preston to Satu Mare | 1,183.82 mi (1,905.17 km) |
| Preston to Scobinti | 1,361.21 mi (2,190.66 km) |
| Preston to Scornicesti | 1,373.31 mi (2,210.13 km) |
| Preston to Sebes | 1,278.42 mi (2,057.42 km) |
| Preston to Seini | 1,201.18 mi (1,933.12 km) |
| Preston to Sfantu-Gheorghe | 1,370.41 mi (2,205.47 km) |
| Preston to Sibiu | 1,308.03 mi (2,105.07 km) |
| Preston to Sighetu Marmatiei | 1,219.52 mi (1,962.62 km) |
| Preston to Sighisoara | 1,317.10 mi (2,119.67 km) |
| Preston to Simeria | 1,260.62 mi (2,028.78 km) |
| Preston to Sinaia | 1,381.06 mi (2,222.61 km) |
