| Preston to Spello | 1,021.15 mi (1,643.38 km) |
| Preston to Spilamberto | 886.22 mi (1,426.23 km) |
| Preston to Spilimbergo | 867.57 mi (1,396.23 km) |
| Preston to Spinea | 873.56 mi (1,405.85 km) |
| Preston to Spoleto | 1,034.27 mi (1,664.50 km) |
| Preston to Spoltore | 1,096.30 mi (1,764.33 km) |
| Preston to Spresiano | 862.24 mi (1,387.64 km) |
| Preston to Squinzano | 1,332.43 mi (2,144.34 km) |
| Preston to Statte | 1,297.15 mi (2,087.56 km) |
| Preston to Stezzano | 784.32 mi (1,262.24 km) |
| Preston to Strada | 947.04 mi (1,524.11 km) |
| Preston to Stradella | 804.18 mi (1,294.21 km) |
| Preston to Striano | 1,199.64 mi (1,930.64 km) |
| Preston to Subiaco | 1,092.50 mi (1,758.21 km) |
| Preston to Sulmona | 1,111.65 mi (1,789.02 km) |
