| Preston to Savignano sul Rubicone | 953.35 mi (1,534.27 km) |
| Preston to Savona | 824.34 mi (1,326.64 km) |
| Preston to Scafati | 1,201.90 mi (1,934.27 km) |
| Preston to Scalea | 1,293.70 mi (2,082.01 km) |
| Preston to Scandiano | 872.86 mi (1,404.73 km) |
| Preston to Scandicci | 933.78 mi (1,502.77 km) |
| Preston to Schio | 835.83 mi (1,345.14 km) |
| Preston to Sciacca | 1,350.66 mi (2,173.68 km) |
| Preston to Scicli | 1,437.40 mi (2,313.28 km) |
| Preston to Scordia | 1,411.16 mi (2,271.04 km) |
| Preston to Scorze | 867.90 mi (1,396.75 km) |
| Preston to Sedico | 840.92 mi (1,353.33 km) |
| Preston to Sedriano | 772.41 mi (1,243.08 km) |
| Preston to Segni | 1,103.98 mi (1,776.68 km) |
| Preston to Segrate | 781.94 mi (1,258.41 km) |
