| Preston to Santa Venerina | 1,396.53 mi (2,247.50 km) |
| Preston to Santeramo in Colle | 1,270.38 mi (2,044.47 km) |
| Preston to Santo Stefano di Magra | 873.24 mi (1,405.34 km) |
| Preston to Santo Stino di Livenza | 879.48 mi (1,415.39 km) |
| Preston to Sarezzo | 801.53 mi (1,289.93 km) |
| Preston to Sarno | 1,201.18 mi (1,933.11 km) |
| Preston to Saronno | 766.82 mi (1,234.08 km) |
| Preston to Sarzana | 877.28 mi (1,411.84 km) |
| Preston to Sassari | 1,041.04 mi (1,675.38 km) |
| Preston to Sasso Marconi | 900.62 mi (1,449.41 km) |
| Preston to Sassuolo | 878.07 mi (1,413.12 km) |
| Preston to Sava | 1,318.18 mi (2,121.40 km) |
| Preston to Saviano | 1,192.52 mi (1,919.17 km) |
| Preston to Savigliano | 781.68 mi (1,257.99 km) |
| Preston to Savignano sul Panaro | 889.41 mi (1,431.37 km) |
