| Prescot to Southern Pines (North Carolina) | 3,789.76 mi (6,099.03 km) |
| Prescot to Southfield (Michigan) | 3,595.11 mi (5,785.77 km) |
| Prescot to Southgate (Michigan) | 3,605.57 mi (5,802.60 km) |
| Prescot to Southlake (Texas) | 4,593.60 mi (7,392.69 km) |
| Prescot to Spanaway (Washington) | 4,641.65 mi (7,470.01 km) |
| Prescot to Spanish Fork (Utah) | 4,716.70 mi (7,590.80 km) |
| Prescot to Spanish Lake (Missouri) | 4,034.21 mi (6,492.44 km) |
| Prescot to Spanish Springs (Nevada) | 4,990.33 mi (8,031.16 km) |
| Prescot to Sparks (Nevada) | 4,996.49 mi (8,041.07 km) |
| Prescot to Spartanburg (South Carolina) | 3,902.50 mi (6,280.46 km) |
| Prescot to Spearfish (South Dakota) | 4,228.97 mi (6,805.87 km) |
| Prescot to Speedway (Indiana) | 3,835.18 mi (6,172.13 km) |
| Prescot to Spencer (Iowa) | 4,000.38 mi (6,438.00 km) |
| Prescot to Spokane (Washington) | 4,474.11 mi (7,200.38 km) |
| Prescot to Spokane Valley (Washington) | 4,468.82 mi (7,191.88 km) |
