| Prescot to Olympia Heights (Florida) | 4,306.20 mi (6,930.16 km) |
| Prescot to Omaha (Nebraska) | 4,125.91 mi (6,640.01 km) |
| Prescot to On Top of the World Designated Place (Florida) | 4,210.66 mi (6,776.40 km) |
| Prescot to Onalaska (Wisconsin) | 3,823.43 mi (6,153.22 km) |
| Prescot to Oneida (New York) | 3,275.42 mi (5,271.28 km) |
| Prescot to Oneonta (New York) | 3,279.42 mi (5,277.72 km) |
| Prescot to Ontario (California) | 5,248.91 mi (8,447.31 km) |
| Prescot to Ontario (Oregon) | 4,663.54 mi (7,505.25 km) |
| Prescot to Opa-locka (Florida) | 4,293.63 mi (6,909.93 km) |
| Prescot to Opelika (Alabama) | 4,153.46 mi (6,684.35 km) |
| Prescot to Opelousas (Louisiana) | 4,526.85 mi (7,285.26 km) |
| Prescot to Orange (California) | 5,269.30 mi (8,480.13 km) |
| Prescot to Orange (Texas) | 4,613.19 mi (7,424.22 km) |
| Prescot to Orange City (Florida) | 4,178.97 mi (6,725.40 km) |
| Prescot to Orangeburg (South Carolina) | 3,931.99 mi (6,327.93 km) |
