| Portsmouth to Storm Lake (Iowa) | 4,183.41 mi (6,732.54 km) |
| Portsmouth to Storrs (Connecticut) | 3,318.60 mi (5,340.78 km) |
| Portsmouth to Stoughton (Wisconsin) | 3,946.72 mi (6,351.64 km) |
| Portsmouth to Stow (Ohio) | 3,720.15 mi (5,987.00 km) |
| Portsmouth to Streamwood (Illinois) | 3,947.84 mi (6,353.43 km) |
| Portsmouth to Streator (Illinois) | 4,014.16 mi (6,460.17 km) |
| Portsmouth to Streetsboro (Ohio) | 3,713.82 mi (5,976.81 km) |
| Portsmouth to Strongsville (Ohio) | 3,730.06 mi (6,002.96 km) |
| Portsmouth to Stuart (Florida) | 4,326.39 mi (6,962.65 km) |
| Portsmouth to Stuarts Draft (Virginia) | 3,762.71 mi (6,055.50 km) |
| Portsmouth to Sturgis (Michigan) | 3,850.56 mi (6,196.88 km) |
| Portsmouth to Suamico (Wisconsin) | 3,826.06 mi (6,157.45 km) |
| Portsmouth to Sudley (Virginia) | 3,664.75 mi (5,897.85 km) |
| Portsmouth to Suffern (New York) | 3,425.69 mi (5,513.11 km) |
| Portsmouth to Suffolk (Virginia) | 3,722.47 mi (5,990.74 km) |
