| Port Talbot to Southern Pines (North Carolina) | 3,779.56 mi (6,082.62 km) |
| Port Talbot to Southfield (Michigan) | 3,606.43 mi (5,803.99 km) |
| Port Talbot to Southgate (Michigan) | 3,616.20 mi (5,819.72 km) |
| Port Talbot to Southlake (Texas) | 4,607.54 mi (7,415.12 km) |
| Port Talbot to Spanaway (Washington) | 4,712.11 mi (7,583.41 km) |
| Port Talbot to Spanish Fork (Utah) | 4,763.69 mi (7,666.42 km) |
| Port Talbot to Spanish Lake (Missouri) | 4,047.95 mi (6,514.54 km) |
| Port Talbot to Spanish Springs (Nevada) | 5,047.95 mi (8,123.89 km) |
| Port Talbot to Sparks (Nevada) | 5,054.07 mi (8,133.74 km) |
| Port Talbot to Spartanburg (South Carolina) | 3,895.84 mi (6,269.75 km) |
| Port Talbot to Spearfish (South Dakota) | 4,272.22 mi (6,875.47 km) |
| Port Talbot to Speedway (Indiana) | 3,845.06 mi (6,188.02 km) |
| Port Talbot to Spencer (Iowa) | 4,029.60 mi (6,485.02 km) |
| Port Talbot to Spokane (Washington) | 4,539.35 mi (7,305.37 km) |
| Port Talbot to Spokane Valley (Washington) | 4,533.82 mi (7,296.48 km) |
