| Port Lavaca to Storm Lake (Iowa) | 972.32 mi (1,564.80 km) |
| Port Lavaca to Storrs (Connecticut) | 1,641.20 mi (2,641.25 km) |
| Port Lavaca to Stoughton (Wisconsin) | 1,070.95 mi (1,723.53 km) |
| Port Lavaca to Stow (Ohio) | 1,218.80 mi (1,961.46 km) |
| Port Lavaca to Streamwood (Illinois) | 1,040.07 mi (1,673.83 km) |
| Port Lavaca to Streator (Illinois) | 969.58 mi (1,560.38 km) |
| Port Lavaca to Streetsboro (Ohio) | 1,225.14 mi (1,971.67 km) |
| Port Lavaca to Strongsville (Ohio) | 1,209.49 mi (1,946.48 km) |
| Port Lavaca to Stuart (Florida) | 1,004.36 mi (1,616.37 km) |
| Port Lavaca to Stuarts Draft (Virginia) | 1,202.41 mi (1,935.09 km) |
| Port Lavaca to Sturgis (Michigan) | 1,106.80 mi (1,781.22 km) |
| Port Lavaca to Suamico (Wisconsin) | 1,202.48 mi (1,935.21 km) |
| Port Lavaca to Sudley (Virginia) | 1,300.83 mi (2,093.48 km) |
| Port Lavaca to Suffern (New York) | 1,532.17 mi (2,465.79 km) |
| Port Lavaca to Suffolk (Virginia) | 1,286.21 mi (2,069.96 km) |
