| Port Lavaca to Oskaloosa (Iowa) | 904.05 mi (1,454.93 km) |
| Port Lavaca to Oswego (Illinois) | 1,015.76 mi (1,634.72 km) |
| Port Lavaca to Oswego (New York) | 1,513.99 mi (2,436.54 km) |
| Port Lavaca to Otsego (Minnesota) | 1,161.96 mi (1,870.00 km) |
| Port Lavaca to Ottawa (Illinois) | 983.60 mi (1,582.95 km) |
| Port Lavaca to Ottawa (Kansas) | 694.08 mi (1,117.02 km) |
| Port Lavaca to Ottumwa (Iowa) | 889.18 mi (1,431.00 km) |
| Port Lavaca to Overland (Missouri) | 783.37 mi (1,260.70 km) |
| Port Lavaca to Overland Park (Kansas) | 718.16 mi (1,155.77 km) |
| Port Lavaca to Overlea (Maryland) | 1,365.65 mi (2,197.80 km) |
| Port Lavaca to Oviedo (Florida) | 935.68 mi (1,505.83 km) |
| Port Lavaca to Owasso (Oklahoma) | 531.95 mi (856.09 km) |
| Port Lavaca to Owatonna (Minnesota) | 1,085.40 mi (1,746.78 km) |
| Port Lavaca to Owensboro (Kentucky) | 836.36 mi (1,346.00 km) |
| Port Lavaca to Owings Mills (Maryland) | 1,354.12 mi (2,179.25 km) |
