| Port Lavaca to Enterprise (Nevada) | 1,197.43 mi (1,927.08 km) |
| Port Lavaca to Enumclaw (Washington) | 1,871.00 mi (3,011.09 km) |
| Port Lavaca to Ephrata (Pennsylvania) | 1,407.58 mi (2,265.28 km) |
| Port Lavaca to Erie (Colorado) | 922.63 mi (1,484.84 km) |
| Port Lavaca to Erie (Pennsylvania) | 1,314.40 mi (2,115.32 km) |
| Port Lavaca to Erlanger (Kentucky) | 994.90 mi (1,601.13 km) |
| Port Lavaca to Escanaba (Michigan) | 1,292.50 mi (2,080.08 km) |
| Port Lavaca to Escondido (California) | 1,249.61 mi (2,011.06 km) |
| Port Lavaca to Española (New Mexico) | 750.50 mi (1,207.81 km) |
| Port Lavaca to Essex (Maryland) | 1,367.19 mi (2,200.28 km) |
| Port Lavaca to Essex Junction (Vermont) | 1,693.60 mi (2,725.58 km) |
| Port Lavaca to Estelle (Louisiana) | 402.42 mi (647.64 km) |
| Port Lavaca to Estero (Florida) | 920.73 mi (1,481.78 km) |
| Port Lavaca to Euclid (Ohio) | 1,234.33 mi (1,986.46 km) |
| Port Lavaca to Eufaula (Alabama) | 721.25 mi (1,160.74 km) |
