| Port Huron to Yonkers (New York) | 462.02 mi (743.56 km) |
| Port Huron to Yorba Linda (California) | 1,995.89 mi (3,212.07 km) |
| Port Huron to York (Pennsylvania) | 361.46 mi (581.71 km) |
| Port Huron to Yorktown (Indiana) | 250.23 mi (402.71 km) |
| Port Huron to Yorkville (Illinois) | 320.42 mi (515.67 km) |
| Port Huron to Youngstown (Ohio) | 159.31 mi (256.39 km) |
| Port Huron to Youngsville (Louisiana) | 1,034.80 mi (1,665.36 km) |
| Port Huron to Ypsilanti (Michigan) | 78.82 mi (126.85 km) |
| Port Huron to Yuba City (California) | 2,040.75 mi (3,284.27 km) |
| Port Huron to Yucaipa (California) | 1,954.49 mi (3,145.45 km) |
| Port Huron to Yucca Valley (California) | 1,920.33 mi (3,090.47 km) |
| Port Huron to Yukon (Oklahoma) | 966.27 mi (1,555.07 km) |
| Port Huron to Yulee (Florida) | 854.45 mi (1,375.10 km) |
| Port Huron to Yuma (Arizona) | 1,879.94 mi (3,025.48 km) |
| Port Huron to Zachary (Louisiana) | 977.04 mi (1,572.39 km) |
