| Port Huron to University Place (Washington) | 1,955.85 mi (3,147.63 km) |
| Port Huron to Upland (California) | 1,982.72 mi (3,190.88 km) |
| Port Huron to Upper Arlington (Ohio) | 206.76 mi (332.75 km) |
| Port Huron to Upper Grand Lagoon (Florida) | 903.85 mi (1,454.61 km) |
| Port Huron to Upper Montclair (New Jersey) | 448.39 mi (721.61 km) |
| Port Huron to Urbana (Illinois) | 357.68 mi (575.63 km) |
| Port Huron to Urbana (Maryland) | 366.01 mi (589.03 km) |
| Port Huron to Urbana (Ohio) | 209.87 mi (337.75 km) |
| Port Huron to Urbandale (Iowa) | 586.45 mi (943.80 km) |
| Port Huron to Utica (New York) | 364.21 mi (586.14 km) |
| Port Huron to Uvalde (Texas) | 1,351.89 mi (2,175.65 km) |
| Port Huron to Vacaville (California) | 2,076.51 mi (3,341.82 km) |
| Port Huron to Vadnais Heights (Minnesota) | 547.09 mi (880.46 km) |
| Port Huron to Vail (Arizona) | 1,712.78 mi (2,756.45 km) |
| Port Huron to Valdosta (Georgia) | 839.50 mi (1,351.05 km) |
