| Port Huron to St. Simons (Georgia) | 817.66 mi (1,315.90 km) |
| Port Huron to Stafford (Texas) | 1,174.09 mi (1,889.52 km) |
| Port Huron to Stallings (North Carolina) | 552.27 mi (888.79 km) |
| Port Huron to Stamford (Connecticut) | 473.52 mi (762.05 km) |
| Port Huron to Stanford (California) | 2,111.14 mi (3,397.54 km) |
| Port Huron to Stanton (California) | 2,010.01 mi (3,234.79 km) |
| Port Huron to Star (Idaho) | 1,699.74 mi (2,735.47 km) |
| Port Huron to Starkville (Mississippi) | 743.16 mi (1,195.99 km) |
| Port Huron to State College (Pennsylvania) | 280.06 mi (450.72 km) |
| Port Huron to Staten Island (New York) | 457.85 mi (736.84 km) |
| Port Huron to Statesboro (Georgia) | 729.46 mi (1,173.95 km) |
| Port Huron to Statesville (North Carolina) | 504.29 mi (811.58 km) |
| Port Huron to Staunton (Virginia) | 377.36 mi (607.30 km) |
| Port Huron to Steamboat Springs (Colorado) | 1,264.72 mi (2,035.37 km) |
| Port Huron to Steiner Ranch (Texas) | 1,218.25 mi (1,960.58 km) |
