| Port Huron to Smyrna (Delaware) | 437.12 mi (703.48 km) |
| Port Huron to Smyrna (Georgia) | 639.95 mi (1,029.90 km) |
| Port Huron to Smyrna (Tennessee) | 531.18 mi (854.85 km) |
| Port Huron to Snellville (Georgia) | 636.17 mi (1,023.82 km) |
| Port Huron to Snoqualmie (Washington) | 1,920.82 mi (3,091.26 km) |
| Port Huron to Snyder (Texas) | 1,228.08 mi (1,976.41 km) |
| Port Huron to Socastee (South Carolina) | 668.42 mi (1,075.72 km) |
| Port Huron to Socorro (Texas) | 1,517.72 mi (2,442.53 km) |
| Port Huron to Soddy-Daisy (Tennessee) | 553.43 mi (890.65 km) |
| Port Huron to Solana Beach (California) | 2,000.67 mi (3,219.77 km) |
| Port Huron to Soledad (California) | 2,096.90 mi (3,374.64 km) |
| Port Huron to Solon (Ohio) | 121.52 mi (195.58 km) |
| Port Huron to Somers Point (New Jersey) | 479.46 mi (771.62 km) |
| Port Huron to Somerset (Kentucky) | 423.41 mi (681.41 km) |
| Port Huron to Somerset (New Jersey) | 443.23 mi (713.32 km) |
