| Port Huron to Silver Firs (Washington) | 1,933.05 mi (3,110.94 km) |
| Port Huron to Silver Spring (Maryland) | 394.09 mi (634.22 km) |
| Port Huron to Silver Springs Shores (Florida) | 958.58 mi (1,542.68 km) |
| Port Huron to Silverdale (Washington) | 1,958.95 mi (3,152.63 km) |
| Port Huron to Silverton (Oregon) | 1,989.38 mi (3,201.60 km) |
| Port Huron to Simi Valley (California) | 2,032.62 mi (3,271.19 km) |
| Port Huron to Simpsonville (South Carolina) | 570.34 mi (917.87 km) |
| Port Huron to Sioux City (Iowa) | 707.95 mi (1,139.34 km) |
| Port Huron to Sioux Falls (South Dakota) | 719.28 mi (1,157.57 km) |
| Port Huron to Skokie (Illinois) | 277.76 mi (447.01 km) |
| Port Huron to Sleepy Hollow (New York) | 458.32 mi (737.59 km) |
| Port Huron to Slidell (Louisiana) | 965.96 mi (1,554.57 km) |
| Port Huron to Smithfield (North Carolina) | 560.33 mi (901.76 km) |
| Port Huron to Smithfield (Utah) | 1,493.67 mi (2,403.83 km) |
| Port Huron to Smithville (Missouri) | 677.24 mi (1,089.92 km) |
