| Port Huron to Shoreview (Minnesota) | 550.38 mi (885.76 km) |
| Port Huron to Shorewood (Illinois) | 312.19 mi (502.41 km) |
| Port Huron to Shorewood (Wisconsin) | 275.17 mi (442.84 km) |
| Port Huron to Short Hills (New Jersey) | 445.00 mi (716.16 km) |
| Port Huron to Short Pump (Virginia) | 446.94 mi (719.28 km) |
| Port Huron to Show Low (Arizona) | 1,597.72 mi (2,571.27 km) |
| Port Huron to Shreveport (Louisiana) | 953.79 mi (1,534.97 km) |
| Port Huron to Sicklerville (New Jersey) | 445.94 mi (717.67 km) |
| Port Huron to Sidney (Ohio) | 206.34 mi (332.08 km) |
| Port Huron to Sierra Madre (California) | 2,000.65 mi (3,219.74 km) |
| Port Huron to Sierra Vista (Arizona) | 1,712.63 mi (2,756.21 km) |
| Port Huron to Sierra Vista Southeast (Arizona) | 1,712.29 mi (2,755.67 km) |
| Port Huron to Signal Hill (California) | 2,018.69 mi (3,248.76 km) |
| Port Huron to Sikeston (Missouri) | 566.04 mi (910.95 km) |
| Port Huron to Siloam Springs (Arkansas) | 795.70 mi (1,280.56 km) |
