| Port Huron to Shelton (Connecticut) | 490.05 mi (788.66 km) |
| Port Huron to Shelton (Washington) | 1,982.21 mi (3,190.05 km) |
| Port Huron to Shenandoah (Louisiana) | 988.96 mi (1,591.57 km) |
| Port Huron to Shepherdsville (Kentucky) | 385.63 mi (620.61 km) |
| Port Huron to Sheridan (Wyoming) | 1,222.95 mi (1,968.15 km) |
| Port Huron to Sherman (Texas) | 1,002.10 mi (1,612.72 km) |
| Port Huron to Sherrelwood (Colorado) | 1,185.42 mi (1,907.74 km) |
| Port Huron to Sherwood (Arkansas) | 767.82 mi (1,235.68 km) |
| Port Huron to Sherwood (Oregon) | 1,987.99 mi (3,199.36 km) |
| Port Huron to Shiloh (Illinois) | 496.38 mi (798.84 km) |
| Port Huron to Shiloh (Ohio) | 237.66 mi (382.48 km) |
| Port Huron to Shiloh (Pennsylvania) | 358.57 mi (577.06 km) |
| Port Huron to Shirley (New York) | 514.31 mi (827.71 km) |
| Port Huron to Shively (Kentucky) | 374.97 mi (603.45 km) |
| Port Huron to Shoreline (Washington) | 1,942.62 mi (3,126.34 km) |
