| Port Huron to Security-Widefield (Colorado) | 1,196.21 mi (1,925.11 km) |
| Port Huron to Sedalia (Missouri) | 636.23 mi (1,023.92 km) |
| Port Huron to Sedro-Woolley (Washington) | 1,933.46 mi (3,111.61 km) |
| Port Huron to Seguin (Texas) | 1,262.44 mi (2,031.69 km) |
| Port Huron to Selden (New York) | 504.03 mi (811.16 km) |
| Port Huron to Selma (Alabama) | 771.68 mi (1,241.90 km) |
| Port Huron to Selma (California) | 2,005.87 mi (3,228.14 km) |
| Port Huron to Selma (Texas) | 1,275.62 mi (2,052.91 km) |
| Port Huron to Seminole (Florida) | 1,046.15 mi (1,683.62 km) |
| Port Huron to Seven Hills (Ohio) | 117.40 mi (188.94 km) |
| Port Huron to Seven Oaks (South Carolina) | 621.26 mi (999.82 km) |
| Port Huron to Severn (Maryland) | 400.03 mi (643.78 km) |
| Port Huron to Severna Park (Maryland) | 407.28 mi (655.45 km) |
| Port Huron to Sevierville (Tennessee) | 493.88 mi (794.83 km) |
| Port Huron to Seymour (Indiana) | 331.81 mi (534.00 km) |
