| Port Huron to Orangeburg (South Carolina) | 661.14 mi (1,064.00 km) |
| Port Huron to Orangevale (California) | 2,030.65 mi (3,268.02 km) |
| Port Huron to Orchards (Washington) | 1,969.32 mi (3,169.32 km) |
| Port Huron to Orcutt (California) | 2,097.74 mi (3,375.99 km) |
| Port Huron to Oregon (Ohio) | 104.96 mi (168.91 km) |
| Port Huron to Oregon (Wisconsin) | 351.40 mi (565.53 km) |
| Port Huron to Oregon City (Oregon) | 1,976.22 mi (3,180.42 km) |
| Port Huron to Orem (Utah) | 1,514.48 mi (2,437.31 km) |
| Port Huron to Orinda (California) | 2,099.55 mi (3,378.90 km) |
| Port Huron to Orland Park (Illinois) | 292.92 mi (471.41 km) |
| Port Huron to Orlando (Florida) | 1,004.06 mi (1,615.88 km) |
| Port Huron to Ormond Beach (Florida) | 948.35 mi (1,526.22 km) |
| Port Huron to Oro Valley (Arizona) | 1,711.14 mi (2,753.81 km) |
| Port Huron to Oroville (California) | 2,028.39 mi (3,264.38 km) |
| Port Huron to Oshkosh (Wisconsin) | 315.10 mi (507.10 km) |
