| Port Huron to Indianapolis (Indiana) | 293.15 mi (471.77 km) |
| Port Huron to Indianola (Iowa) | 580.17 mi (933.69 km) |
| Port Huron to Indio (California) | 1,924.01 mi (3,096.40 km) |
| Port Huron to Inglewood (California) | 2,022.44 mi (3,254.80 km) |
| Port Huron to Inkster (Michigan) | 65.16 mi (104.87 km) |
| Port Huron to Inver Grove Heights (Minnesota) | 543.40 mi (874.52 km) |
| Port Huron to Inwood (New York) | 476.00 mi (766.05 km) |
| Port Huron to Iona (Florida) | 1,138.02 mi (1,831.46 km) |
| Port Huron to Ionia (Michigan) | 133.13 mi (214.26 km) |
| Port Huron to Iowa City (Iowa) | 473.17 mi (761.49 km) |
| Port Huron to Irmo (South Carolina) | 617.22 mi (993.31 km) |
| Port Huron to Irondale (Alabama) | 690.91 mi (1,111.92 km) |
| Port Huron to Ironton (Ohio) | 307.71 mi (495.20 km) |
| Port Huron to Irvine (California) | 2,003.11 mi (3,223.69 km) |
| Port Huron to Irving (Texas) | 1,053.91 mi (1,696.10 km) |
