| Port Huron to Elyria (Ohio) | 112.27 mi (180.68 km) |
| Port Huron to Emeryville (California) | 2,106.43 mi (3,389.97 km) |
| Port Huron to Emmaus (Pennsylvania) | 395.51 mi (636.51 km) |
| Port Huron to Emporia (Kansas) | 785.73 mi (1,264.51 km) |
| Port Huron to Encinitas (California) | 1,998.94 mi (3,216.98 km) |
| Port Huron to Endicott (New York) | 330.15 mi (531.32 km) |
| Port Huron to Endwell (New York) | 331.94 mi (534.20 km) |
| Port Huron to Englewood (Colorado) | 1,189.20 mi (1,913.84 km) |
| Port Huron to Englewood (Florida) | 1,106.22 mi (1,780.29 km) |
| Port Huron to Englewood (New Jersey) | 458.19 mi (737.38 km) |
| Port Huron to Englewood (Ohio) | 236.15 mi (380.04 km) |
| Port Huron to Enid (Oklahoma) | 935.71 mi (1,505.87 km) |
| Port Huron to Ennis (Texas) | 1,067.32 mi (1,717.68 km) |
| Port Huron to Ensley (Florida) | 900.86 mi (1,449.80 km) |
| Port Huron to Enterprise (Alabama) | 826.63 mi (1,330.33 km) |
