| Port Huron to Delaware (Ohio) | 189.21 mi (304.50 km) |
| Port Huron to Delhi (California) | 2,040.74 mi (3,284.25 km) |
| Port Huron to Delray Beach (Florida) | 1,149.54 mi (1,850.01 km) |
| Port Huron to Deltona (Florida) | 975.01 mi (1,569.13 km) |
| Port Huron to Deming (New Mexico) | 1,562.11 mi (2,513.97 km) |
| Port Huron to Denison (Texas) | 993.66 mi (1,599.15 km) |
| Port Huron to Dent (Ohio) | 286.28 mi (460.73 km) |
| Port Huron to Denton (Texas) | 1,043.32 mi (1,679.07 km) |
| Port Huron to Dentsville (South Carolina) | 620.57 mi (998.71 km) |
| Port Huron to Denver (Colorado) | 1,180.72 mi (1,900.19 km) |
| Port Huron to Depew (New York) | 188.92 mi (304.04 km) |
| Port Huron to Derby (Connecticut) | 492.38 mi (792.41 km) |
| Port Huron to Derby (Kansas) | 864.73 mi (1,391.64 km) |
| Port Huron to Des Moines (Iowa) | 578.91 mi (931.67 km) |
| Port Huron to Des Moines (Washington) | 1,943.81 mi (3,128.25 km) |
