| Port Huron to Shoreham-by-Sea | 3,712.50 mi (5,974.69 km) |
| Port Huron to Shotley Bridge | 3,538.14 mi (5,694.08 km) |
| Port Huron to Shrewsbury | 3,562.14 mi (5,732.72 km) |
| Port Huron to Sidcup | 3,709.26 mi (5,969.48 km) |
| Port Huron to Sidmouth | 3,599.72 mi (5,793.19 km) |
| Port Huron to Sileby | 3,624.65 mi (5,833.31 km) |
| Port Huron to Sittingbourne | 3,736.59 mi (6,013.45 km) |
| Port Huron to Skegness | 3,667.72 mi (5,902.63 km) |
| Port Huron to Skelmersdale | 3,538.66 mi (5,694.92 km) |
| Port Huron to Skipton | 3,556.30 mi (5,723.32 km) |
| Port Huron to Sleaford | 3,643.45 mi (5,863.57 km) |
| Port Huron to Slough | 3,680.01 mi (5,922.40 km) |
| Port Huron to Small Heath | 3,603.54 mi (5,799.33 km) |
| Port Huron to Smethwick | 3,598.29 mi (5,790.89 km) |
| Port Huron to Snaresbrook | 3,701.04 mi (5,956.25 km) |
