| Port Charlotte to Indianapolis (Indiana) | 913.20 mi (1,469.66 km) |
| Port Charlotte to Indianola (Iowa) | 1,186.83 mi (1,910.02 km) |
| Port Charlotte to Indio (California) | 2,076.79 mi (3,342.27 km) |
| Port Charlotte to Inglewood (California) | 2,198.53 mi (3,538.19 km) |
| Port Charlotte to Inkster (Michigan) | 1,059.41 mi (1,704.96 km) |
| Port Charlotte to Inver Grove Heights (Minnesota) | 1,373.00 mi (2,209.63 km) |
| Port Charlotte to Inwood (New York) | 1,055.82 mi (1,699.17 km) |
| Port Charlotte to Iona (Florida) | 34.22 mi (55.07 km) |
| Port Charlotte to Ionia (Michigan) | 1,116.92 mi (1,797.50 km) |
| Port Charlotte to Iowa City (Iowa) | 1,145.10 mi (1,842.86 km) |
| Port Charlotte to Irmo (South Carolina) | 494.28 mi (795.46 km) |
| Port Charlotte to Irondale (Alabama) | 527.62 mi (849.12 km) |
| Port Charlotte to Ironton (Ohio) | 798.04 mi (1,284.32 km) |
| Port Charlotte to Irvine (California) | 2,164.91 mi (3,484.08 km) |
| Port Charlotte to Irving (Texas) | 976.33 mi (1,571.25 km) |
