| Port Charlotte to Des Plaines (Illinois) | 1,089.61 mi (1,753.56 km) |
| Port Charlotte to Desert Hot Springs (California) | 2,095.45 mi (3,372.29 km) |
| Port Charlotte to DeSoto (Texas) | 964.31 mi (1,551.90 km) |
| Port Charlotte to Destin (Florida) | 353.48 mi (568.87 km) |
| Port Charlotte to Destrehan (Louisiana) | 541.48 mi (871.43 km) |
| Port Charlotte to Detroit (Michigan) | 1,064.92 mi (1,713.82 km) |
| Port Charlotte to Diamond Bar (California) | 2,168.45 mi (3,489.78 km) |
| Port Charlotte to Diamond Springs (California) | 2,368.33 mi (3,811.46 km) |
| Port Charlotte to Dickinson (North Dakota) | 1,775.87 mi (2,857.99 km) |
| Port Charlotte to Dickinson (Texas) | 805.76 mi (1,296.74 km) |
| Port Charlotte to Dickson (Tennessee) | 698.67 mi (1,124.40 km) |
| Port Charlotte to Difficult Run (Virginia) | 867.70 mi (1,396.43 km) |
| Port Charlotte to Dinuba (California) | 2,271.63 mi (3,655.83 km) |
| Port Charlotte to Discovery Bay (California) | 2,402.26 mi (3,866.07 km) |
| Port Charlotte to Dix Hills (New York) | 1,077.47 mi (1,734.02 km) |
