| Port Charlotte to Delaware (Ohio) | 920.12 mi (1,480.79 km) |
| Port Charlotte to Delhi (California) | 2,353.84 mi (3,788.14 km) |
| Port Charlotte to Delray Beach (Florida) | 130.27 mi (209.64 km) |
| Port Charlotte to Deltona (Florida) | 143.15 mi (230.38 km) |
| Port Charlotte to Deming (New Mexico) | 1,578.18 mi (2,539.84 km) |
| Port Charlotte to Denison (Texas) | 979.77 mi (1,576.79 km) |
| Port Charlotte to Dent (Ohio) | 855.60 mi (1,376.95 km) |
| Port Charlotte to Denton (Texas) | 994.56 mi (1,600.58 km) |
| Port Charlotte to Dentsville (South Carolina) | 494.26 mi (795.43 km) |
| Port Charlotte to Denver (Colorado) | 1,574.75 mi (2,534.32 km) |
| Port Charlotte to Depew (New York) | 1,116.52 mi (1,796.86 km) |
| Port Charlotte to Derby (Connecticut) | 1,115.37 mi (1,795.01 km) |
| Port Charlotte to Derby (Kansas) | 1,144.15 mi (1,841.33 km) |
| Port Charlotte to Des Moines (Iowa) | 1,199.85 mi (1,930.97 km) |
| Port Charlotte to Des Moines (Washington) | 2,581.67 mi (4,154.80 km) |
