| Poplar Bluff to Altus (Oklahoma) | 519.47 mi (836.00 km) |
| Poplar Bluff to Alum Rock (California) | 1,724.19 mi (2,774.81 km) |
| Poplar Bluff to Alvin (Texas) | 582.49 mi (937.43 km) |
| Poplar Bluff to Amarillo (Texas) | 647.08 mi (1,041.37 km) |
| Poplar Bluff to Amelia (Ohio) | 371.96 mi (598.60 km) |
| Poplar Bluff to American Canyon (California) | 1,740.41 mi (2,800.92 km) |
| Poplar Bluff to American Fork (Utah) | 1,178.63 mi (1,896.82 km) |
| Poplar Bluff to Americus (Georgia) | 478.76 mi (770.48 km) |
| Poplar Bluff to Ames (Iowa) | 401.85 mi (646.71 km) |
| Poplar Bluff to Amherst (Ohio) | 543.06 mi (873.97 km) |
| Poplar Bluff to Ammon (Idaho) | 1,224.61 mi (1,970.81 km) |
| Poplar Bluff to Amsterdam (New York) | 958.37 mi (1,542.34 km) |
| Poplar Bluff to Anacortes (Washington) | 1,809.04 mi (2,911.37 km) |
| Poplar Bluff to Anaheim (California) | 1,555.28 mi (2,502.97 km) |
| Poplar Bluff to Anchorage (Alaska) | 3,007.30 mi (4,839.78 km) |
