| Plattsburgh to Southern Pines (North Carolina) | 727.72 mi (1,171.15 km) |
| Plattsburgh to Southfield (Michigan) | 513.68 mi (826.69 km) |
| Plattsburgh to Southgate (Michigan) | 518.02 mi (833.68 km) |
| Plattsburgh to Southlake (Texas) | 1,502.90 mi (2,418.69 km) |
| Plattsburgh to Spanaway (Washington) | 2,321.74 mi (3,736.48 km) |
| Plattsburgh to Spanish Fork (Utah) | 1,955.41 mi (3,146.93 km) |
| Plattsburgh to Spanish Lake (Missouri) | 952.77 mi (1,533.33 km) |
| Plattsburgh to Spanish Springs (Nevada) | 2,359.59 mi (3,797.40 km) |
| Plattsburgh to Sparks (Nevada) | 2,364.20 mi (3,804.81 km) |
| Plattsburgh to Spartanburg (South Carolina) | 808.84 mi (1,301.70 km) |
| Plattsburgh to Spearfish (South Dakota) | 1,485.08 mi (2,390.01 km) |
| Plattsburgh to Speedway (Indiana) | 735.57 mi (1,183.78 km) |
| Plattsburgh to Spencer (Iowa) | 1,081.87 mi (1,741.10 km) |
| Plattsburgh to Spokane (Washington) | 2,085.37 mi (3,356.09 km) |
| Plattsburgh to Spokane Valley (Washington) | 2,076.37 mi (3,341.59 km) |
