| Pittsburgh to University Place (Washington) | 2,144.94 mi (3,451.94 km) |
| Pittsburgh to Upland (California) | 2,100.72 mi (3,380.79 km) |
| Pittsburgh to Upper Arlington (Ohio) | 165.67 mi (266.61 km) |
| Pittsburgh to Upper Grand Lagoon (Florida) | 780.06 mi (1,255.38 km) |
| Pittsburgh to Upper Montclair (New Jersey) | 304.03 mi (489.29 km) |
| Pittsburgh to Urbana (Illinois) | 433.81 mi (698.14 km) |
| Pittsburgh to Urbana (Maryland) | 159.39 mi (256.51 km) |
| Pittsburgh to Urbana (Ohio) | 200.44 mi (322.58 km) |
| Pittsburgh to Urbandale (Iowa) | 723.40 mi (1,164.20 km) |
| Pittsburgh to Utica (New York) | 305.88 mi (492.26 km) |
| Pittsburgh to Uvalde (Texas) | 1,359.70 mi (2,188.22 km) |
| Pittsburgh to Vacaville (California) | 2,225.41 mi (3,581.45 km) |
| Pittsburgh to Vadnais Heights (Minnesota) | 736.02 mi (1,184.50 km) |
| Pittsburgh to Vail (Arizona) | 1,797.36 mi (2,892.57 km) |
| Pittsburgh to Valdosta (Georgia) | 687.88 mi (1,107.03 km) |
