| Pittsburgh to Storm Lake (Iowa) | 800.51 mi (1,288.29 km) |
| Pittsburgh to Storrs (Connecticut) | 412.87 mi (664.45 km) |
| Pittsburgh to Stoughton (Wisconsin) | 506.72 mi (815.49 km) |
| Pittsburgh to Stow (Ohio) | 91.68 mi (147.55 km) |
| Pittsburgh to Streamwood (Illinois) | 439.76 mi (707.73 km) |
| Pittsburgh to Streator (Illinois) | 465.39 mi (748.98 km) |
| Pittsburgh to Streetsboro (Ohio) | 90.43 mi (145.53 km) |
| Pittsburgh to Strongsville (Ohio) | 114.15 mi (183.70 km) |
| Pittsburgh to Stuart (Florida) | 915.19 mi (1,472.85 km) |
| Pittsburgh to Stuarts Draft (Virginia) | 174.68 mi (281.12 km) |
| Pittsburgh to Sturgis (Michigan) | 298.37 mi (480.18 km) |
| Pittsburgh to Suamico (Wisconsin) | 503.35 mi (810.06 km) |
| Pittsburgh to Sudley (Virginia) | 174.50 mi (280.83 km) |
| Pittsburgh to Suffern (New York) | 308.72 mi (496.84 km) |
| Pittsburgh to Suffolk (Virginia) | 315.25 mi (507.35 km) |
