| Pittsburgh to St. Simons (Georgia) | 644.78 mi (1,037.68 km) |
| Pittsburgh to Stafford (Texas) | 1,152.67 mi (1,855.04 km) |
| Pittsburgh to Stallings (North Carolina) | 370.21 mi (595.80 km) |
| Pittsburgh to Stamford (Connecticut) | 338.86 mi (545.34 km) |
| Pittsburgh to Stanford (California) | 2,255.64 mi (3,630.10 km) |
| Pittsburgh to Stanton (California) | 2,126.96 mi (3,423.01 km) |
| Pittsburgh to Star (Idaho) | 1,871.05 mi (3,011.17 km) |
| Pittsburgh to Starkville (Mississippi) | 685.94 mi (1,103.92 km) |
| Pittsburgh to State College (Pennsylvania) | 113.78 mi (183.12 km) |
| Pittsburgh to Staten Island (New York) | 306.18 mi (492.75 km) |
| Pittsburgh to Statesboro (Georgia) | 561.83 mi (904.17 km) |
| Pittsburgh to Statesville (North Carolina) | 325.32 mi (523.55 km) |
| Pittsburgh to Staunton (Virginia) | 164.98 mi (265.51 km) |
| Pittsburgh to Steamboat Springs (Colorado) | 1,405.94 mi (2,262.64 km) |
| Pittsburgh to Steiner Ranch (Texas) | 1,222.12 mi (1,966.81 km) |
