| Pittsburgh to Security-Widefield (Colorado) | 1,317.93 mi (2,121.00 km) |
| Pittsburgh to Sedalia (Missouri) | 715.46 mi (1,151.42 km) |
| Pittsburgh to Sedro-Woolley (Washington) | 2,127.17 mi (3,423.35 km) |
| Pittsburgh to Seguin (Texas) | 1,260.18 mi (2,028.07 km) |
| Pittsburgh to Selden (New York) | 364.36 mi (586.38 km) |
| Pittsburgh to Selma (Alabama) | 678.59 mi (1,092.09 km) |
| Pittsburgh to Selma (California) | 2,141.71 mi (3,446.74 km) |
| Pittsburgh to Selma (Texas) | 1,275.94 mi (2,053.43 km) |
| Pittsburgh to Seminole (Florida) | 884.86 mi (1,424.04 km) |
| Pittsburgh to Seven Hills (Ohio) | 109.90 mi (176.86 km) |
| Pittsburgh to Seven Oaks (South Carolina) | 446.29 mi (718.23 km) |
| Pittsburgh to Severn (Maryland) | 196.09 mi (315.58 km) |
| Pittsburgh to Severna Park (Maryland) | 203.67 mi (327.77 km) |
| Pittsburgh to Sevierville (Tennessee) | 370.06 mi (595.56 km) |
| Pittsburgh to Seymour (Indiana) | 330.85 mi (532.45 km) |
