| Pittsburgh to San Diego (California) | 2,108.84 mi (3,393.85 km) |
| Pittsburgh to San Diego Country Estates (California) | 2,086.04 mi (3,357.15 km) |
| Pittsburgh to San Dimas (California) | 2,108.80 mi (3,393.79 km) |
| Pittsburgh to San Fernando (California) | 2,136.90 mi (3,439.01 km) |
| Pittsburgh to San Francisco (California) | 2,262.83 mi (3,641.67 km) |
| Pittsburgh to San Gabriel (California) | 2,124.41 mi (3,418.91 km) |
| Pittsburgh to San Germán (Puerto Rico) | 1,725.66 mi (2,777.19 km) |
| Pittsburgh to San Jacinto (California) | 2,074.37 mi (3,338.37 km) |
| Pittsburgh to San Jose (California) | 2,241.77 mi (3,607.78 km) |
| Pittsburgh to San Juan (Puerto Rico) | 1,732.83 mi (2,788.72 km) |
| Pittsburgh to San Juan (Texas) | 1,433.44 mi (2,306.90 km) |
| Pittsburgh to San Juan Capistrano (California) | 2,117.51 mi (3,407.81 km) |
| Pittsburgh to San Leandro (California) | 2,249.08 mi (3,619.55 km) |
| Pittsburgh to San Lorenzo (California) | 2,248.43 mi (3,618.50 km) |
| Pittsburgh to San Luis (Arizona) | 1,992.34 mi (3,206.36 km) |
